Women comprise a majority of Dr. Oz’s audience. The vast majority of women would like to shed weight. Which is a match made in heaven, a marketer’s dream. And Oz has never hesitated to exploit that fact to improve audience share, playing fast and loose with sensationalized evidence rather than giving his viewers science-based advice.
Garcinia cambogia extract (GCE) comes from a tropical fruit from India and Southeast Asia. The active component, see here, is considered to block fat and suppress hunger.
Garcinia cambogia extract (GCE) originates from a tropical fruit from India and Southeast Asia. The active ingredient, hydroxycitric acid (HCA), has been said to bar fat and suppress the appetite.
Dr. Oz has promoted a series of weight loss supplements on his show. Raspberry ketones were presented like a fat-busting miracle, then green coffee bean extract was touted as “magic,” “staggering,” and “unprecedented.” And today both of those miracles have apparently been superseded by a level greater miracle: Garcinia cambogia extract.
Dr. Oz calls it “The newest, fastest fat buster.” A method without “spending every waking moment exercising and dieting.” “Triples your weight loss.” “The most exciting breakthrough in natural weight reduction so far.” “The Holy Grail.” Oz claims that “Revolutionary new information says it may be the magic ingredient that permits you to lose fat without diet or exercise.”
Everything that sounds too good to be true, in fact it is. Garcinia probably does work to some degree to further improve weight loss, but the evidence doesn’t set out to justify such grandiose claims.
Garcinia cambogia extract (GCE) comes from a tropical fruit grown in India and Southeast Asia. The active component continues to be identified: hydroxycitric acid (HCA). It is known to block fat and suppress hunger. It inhibits a vital enzyme, citrate lyase, how the body demands to create fat from carbohydrates. It suppresses appetite by increasing serotonin levels; low serotonin levels are related to depression and emotional or reactive eating.
It allegedly decreases tummy fat, suppresses appetite, controls emotional eating, and changes body composition by increasing muscle. It doesn’t just produce weight reduction, however it improves overall wellness. It is known to diminish cholesterol, LDL, and triglycerides by 10-30% as well as raise levels of the “good cholesterol” HDL.
A completely independent analysis learned that some brands contain much less active component than claimed. Consumers are advised to look for at least 50% GCE with potassium however with no fillers, binders, or artificial ingredients.
It must be taken on empty stomach 30-60 minutes before dinner. Results increase with dosage, but doses over 3 000 mg per day should be cleared with your doctor.
Dr. Oz recommends a dose of 500-1000 mg of pure garcinia cambogia before each meal. (Some experts believe the potassium salt is much more effective than other formulations.) He says never to bring it in case you are pregnant or breastfeeding, or in case you have Alzheimer’s disease or another kinds of dementia, since it can worsen dementia. When you have diabetes, it can cause hypoglycemia, and when you are over a statin, it could increase the danger of harmful negative effects like rhabdomyolysis or muscle degradation.
Oz contradicts himself: he suggests that it can produce weight loss without diet or exercise, yet he clearly recommends it be used together with exercise and properly portioned meals.
With Dr. Oz’s track record, I had been reluctant to simply accept his word for that wonders of Garcinia. I traveled to PubMed, wherein a seek out hydroxycitric acid brought up 64 articles. Some were irrelevant, and the relevant ones included a lot of animal studies and a smaller variety of human studies with inconsistent results.
Guinea pigs over a high cholesterol levels diet who are given another Garcinia species (atriviridis) had a tendency to decrease lipid composition levels and fat deposition within the aorta. HCA caused congenital defects in rats. Another rat study found out that it decreased body weight gain and visceral fat accumulation by reducing food consumption but had no lasting beneficial effects on hypertriglyceridemia and hyperinsulinemia. An additional rat study showed that it suppressed unwanted fat accumulation but was toxic to the testes.
To attempt to appear sensible from the inconsistent results, Onakpoya et al. did a systematic article on the published randomized controlled trials (RCTs) by 2011. Their analysis found a tiny, statistically significant difference in weight loss (1.75 kg vs .88 kg, under 2 pounds). They commented how the studies all had methodological weaknesses, so these results could possibly be because of GIGO (garbage in/garbage out). Both studies together with the best methodology found 84dexcpky statistically significant difference from placebo. Adverse events were two times as normal with Garcinia (headache, nausea, upper respiratory and gastrointestinal symptoms). The authors concluded:
Evidence from RCTs suggests that Garcinia extracts/HCA generate weight reduction around the short-run. However, the magnitude on this effect is small, has stopped being statistically significant when only rigorous RCTs are thought, as well as its clinical relevance seems questionable.
Oz featured the patient testimonial about the show from the woman who had lost ten pounds in 4 months. She started noticing results after a week; she reported that her sugar cravings were decreased, she had more energy, and she went down a gown size from 10 to 8. She had no unwanted effects. Says she was in a plateau and wanted a jump-start.
At this stage, I don’t think we can reliably say whether pure garcinia cambogia weight loss has a clinically relevant edge on simple calorie reduction and physical activity. It seems to be safe, and yes it may have a role in assisting patients shed weight by assisting motivation and enlisting placebo effects.
Dr. Oz’s popularity is enduring, but diet fads aren’t. I confidently expect another “miracle” to supplant Garcinia in the Land of Oz in the not-too-distant future.